Real Madrid won the El Clasico to go top of La Liga on Saturday night, but the victory over Barcelona came at a price.
Captain Sergio Ramos will not recover from his calf injury in time for the second leg, while Raphael Varane’s involvement is also doubtful after he tested positive for coronavirus.
Adding to Real Madrid’s defensive injury woes, Lucas Vazquez looks likely to miss the trip to the Premier League champions.
Though he is a natural winger, the Spain international has spent the majority of the season at right-back due to Dani Carvajal’s ongoing injury woes.
He is set for a scan on the issue and a decision over his fitness will be made on Monday, the day before Real Madrid fly to Liverpool, according to Spanish outlet Marca .
The news of the 29-year-old’s injury leaves Zidane with a selection conundrum, and the Frenchman was downbeat despite his side’s 2-1 El Clasico victory.