Sunday's final game of the Premier League season at home to Cardiff could really be the start of the Ole Gunnar Solskjaer era.
And that could include the loss of several first-team players. One of those will be club captain Antonio Valencia.
Valencia isn't the only one, these other players also will potentially be saying their goodbyes.
David de Gea
The goalkeeper wants more money for being out of the Champions League, and United might be better off not doing that sort of thing any more.
Is this his last game for the Frenchman as he seems to be distracted at the moment, and those rumours of a possible move to Real Madrid – which I think he really wants – simply won't go away.
It's best he moves on, but who'll take him? Is this his last game? Form an orderly queue.
He recently-turned-31-year-old and his deal will expire in the summer. His age is one of the things counting against him getting a new one.
Is this his last game? Probably.
Ever since the Norwegian made it clear that Marcus Rashford was his preferred central striker, A parting of the ways is looking possible in the summer.
The Belgian – or more particularly his Italian agent – seems to be aligning himself with a move to Serie A.
Everything you can think of seems to be running out for the Argentinean defender at Old Trafford, and this will surely be the last time we see him in a United jersey.
He'll most likely be on the first flight out of Manchester Airport.
The Spaniard will join Paris Saint-Germain in the summer, and it all just seems like a bit of a waste really.
This hasn't been a happy season for the Red Devils, but especially for him.
Is this his last game? Should it be, but where will he end up?
It has been easy to forget about the Italian for some time now, but his four-year stay at Old Trafford will surely be coming to an end in the summer following another underwhelming season.
This article was most recently revised and updated 7 months ago