Real Madrid would look to continue from where they left off last weekend following their 4-1 triumph away at Alaves.
However, they would be without a number of important personnel ahead of the second La Liga match of the season.
Real's quartet of Dani Ceballos, Ferland Mendy, Dani Carvajal and Toni Kroos are all out injured. Marcelo is a doubt due to the issue that caused him to miss the Alaves victory last week.
Also, the Galacticos would not be able to utilize the services of the exemplary Luka Modric owing to the thigh injury he suffered during Friday's training.
Madrid boss Carlo Ancelotti have a big decision to make in midfield, Casemiro and Federico Valverde are certain starters, but Modric's absence could see Isco come into the team.
The Spaniard could feature in the midfield three. Marcelo's absence should see David Alaba keep his place at left back while Gareth Bale possibly has a huge role to play for Real Madrid this season.
Gareth Bale was listed in a front three with Eden Hazard and Karim Benzema against Alaves and it would not be a surprise if Ancelotti selects the Wales Superstar in the first eleven.
Vinicius Junior, Rodrygo and Marco Asensio are also attacking options for Real Madrid, while Luka Jovic came from the substitute bench at the weekend and is also in contention for a starting place.
Real Madrid possible starting lineup:
Thibaut Courtois; Lukas Vasquez, Nacho Fernandez, Eder Militao, David Alaba; Federico Valverde, Casemiro, Isco, Alarcon; Gareth Bale, Karim Benzema, Eden Hazard.